Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.65 |
| ▸ | ACE | P12821 | 4/20 | 0.64 |
| ▸ | ITGB2 | P05107 | 6/20 | 0.64 |
| ▸ | ICAM1 | P05362 | 6/20 | 0.64 |
| ▸ | ITGAL | P20701 | 6/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL2597753 | 1.00 | ERAP2 (0.65) | ERAP2ALOX15P2RY14ACEITGB2 | |
| SCHEMBL1407979 | 0.97 | ALOX15 (0.68) | ERAP2ALOX15P2RY14ACEITGB2 | |
| SCHEMBL30051539 | 0.97 | ALOX15 (0.68) | ERAP2ALOX15P2RY14ACEITGB2 | |
| SCHEMBL1407978 | 0.97 | ALOX15 (0.68) | ERAP2ALOX15P2RY14ACEITGB2 | |
| Water SCHEMBL28029902 | 0.96 | ERAP2 (0.67) | ERAP2ALOX15P2RY14ACEITGB2 | |
| Water SCHEMBL28029903 | 0.96 | ERAP2 (0.67) | ERAP2ALOX15P2RY14ACEITGB2 | |
| SCHEMBL30051742 | 0.93 | ACE (0.68) | ERAP2ALOX15P2RY14ACEITGB2 | |
| SCHEMBL31238592 | 0.90 | ECE1 (0.64) | ERAP2ALOX15P2RY14ACEITGB2 | |
| SCHEMBL15757296 | 0.90 | ERAP2 (0.62) | ERAP2ALOX15P2RY14ACEITGB2 | |
| SCHEMBL15757291 | 0.90 | ERAP2 (0.62) | ERAP2ALOX15P2RY14ACEITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011146683-A1 | METHODS AND REAGENTS FOR METABOLOMICS AND HISTOLOGY IN A BIOLOGICAL SAMPLE AND A KIT FOR THE SAME | METABOLON, INC. (US) | 2011-11-24 | — | — | WO | disclosed |