Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 12/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29043900 | 0.93 | USP1 (0.42) | USP1PTGS2PTGS1ADRB2 | |
| SCHEMBL30462024 | 0.93 | USP1 (0.42) | USP1PTGS2PTGS1ADRB2 | |
| SCHEMBL25978767 | 0.87 | USP1 (0.42) | USP1ADRB2 | |
| SCHEMBL27031678 | 0.86 | USP1 (0.41) | USP1PTGS2 | |
| SCHEMBL29878934 | 0.86 | USP1 (0.41) | USP1PTGS2 | |
| SCHEMBL30461986 | 0.86 | USP1 (0.39) | USP1PTGS2PTGS1ADRB2 | |
| SCHEMBL29043885 | 0.86 | USP1 (0.39) | USP1PTGS2PTGS1ADRB2 | |
| SCHEMBL25978533 | 0.86 | USP1 (0.50) | USP1 | |
| SCHEMBL25978576 | 0.84 | USP1 (0.43) | USP1PTGS2PTGS1 | |
| SCHEMBL31155901 | 0.84 | USP1 (0.45) | USP1PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023148643-A1 | FUSED BICYCLIC HETEROCYCLYL COMPOUNDS AS USP1 INHIBITORS | AURIGENE ONCOLOGY LIMITED (IN) | 2023-08-10 | — | — | WO | disclosed |