SCHEMBL2597893

SCHEMBL2597893

CC(C(=O)O)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)c(C(=O)N(C)C)c1

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KLRK1 P26718 5/20 0.52
MICA Q29983 5/20 0.52
RAET1L Q5VY80 4/20 0.52
AKR1C3 P42330 2/20 0.51
AKR1C2 P52895 2/20 0.51
MTTP P55157 13/20 0.51
APOB P04114 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14031471 0.85 KLRK1 (0.52) KLRK1MICARAET1LMTTPAPOB
SCHEMBL403174 0.84 MTTP (0.53) KLRK1MICARAET1LMTTPAPOB
SCHEMBL2597850 0.82 PPARG (0.53) KLRK1MICARAET1LMTTPAPOB
SCHEMBL402631 0.82 MTTP (0.49) KLRK1MICARAET1LMTTPAPOB
SCHEMBL401799 0.81 MTTP (0.48) KLRK1MICARAET1LMTTPAPOB
SCHEMBL6795000 0.81 MTTP (0.54) KLRK1MICARAET1LAKR1C3AKR1C2
SCHEMBL400773 0.80 PPARA (0.55) KLRK1MICARAET1LMTTPAPOB
SCHEMBL14031572 0.80 MTTP (0.53) KLRK1MICARAET1LMTTPAPOB
SCHEMBL5064986 0.80 MTTP (0.48) KLRK1MICARAET1LMTTPAPOB
SCHEMBL402135 0.80 MTTP (0.51) KLRK1MICARAET1LMTTPAPOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011145022-A1 2-PHENYL BENZOYLAMIDES PFIZER INC. (US) 2011-11-24 WO disclosed