Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 12/20 | 0.48 |
| ▸ | APOB | P04114 | 5/20 | 0.48 |
| ▸ | KLRK1 | P26718 | 5/20 | 0.48 |
| ▸ | MICA | Q29983 | 5/20 | 0.48 |
| ▸ | RAET1L | Q5VY80 | 4/20 | 0.48 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL402631 | 0.91 | MTTP (0.49) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL14031471 | 0.87 | KLRK1 (0.52) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL403174 | 0.86 | MTTP (0.53) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL2597850 | 0.82 | PPARG (0.53) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL2597893 | 0.81 | KLRK1 (0.52) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL400773 | 0.80 | PPARA (0.55) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL13580512 | 0.80 | MTTP (0.50) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL14031528 | 0.80 | NTRK1 (0.50) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL14031572 | 0.79 | MTTP (0.53) | MTTPAPOBKLRK1MICARAET1L | |
| SCHEMBL5064986 | 0.79 | MTTP (0.48) | MTTPAPOBKLRK1MICARAET1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101774-B2 | Ester derivatives and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2012-01-24 | — | — | US | disclosed |