SCHEMBL25979231

SCHEMBL25979231

CC(C)NC(C)(C)C(=O)C(C)(C)CC(C)(C)CN

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25979247 0.74 KDM4E (0.43) KDM4ECYP2D6
SCHEMBL14275442 0.69 L3MBTL1 (0.31)
SCHEMBL11981935 0.68 KDM4E (0.50) KDM4ECYP2D6
SCHEMBL19493224 0.68 KDM4E (0.44) KDM4ECYP2D6
SCHEMBL14094680 0.68 KDM4E (0.44) KDM4ECYP2D6
SCHEMBL8153132 0.67 KDM4E (0.40) KDM4ECYP2D6
SCHEMBL19706425 0.67 KDM4E (0.40) KDM4ECYP2D6
SCHEMBL15499322 0.67 KDM4E (0.40) KDM4ECYP2D6
SCHEMBL23056883 0.66 PIK3CD (0.31)
SCHEMBL12878317 0.66 KDM4E (0.32) KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES ASGR1, LAMP2, FCGR2A KDM4E 4034/4885CYP2D6 4035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.