Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 7/20 | 0.41 |
| ▸ | CDK2 | P24941 | 6/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.40 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.40 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21011193 | 0.85 | KDM4E (0.44) | CDK1CDK2CCNB1CCNE1CDK9 | |
| SCHEMBL17282460 | 0.85 | CDK2 (0.44) | CDK1CDK2CCNB1CCNE1KDM4E | |
| SCHEMBL25469093 | 0.83 | KDM4E (0.43) | CDK1CDK2CCNB1CCNE1CDK9 | |
| SCHEMBL21011259 | 0.83 | TDP1 (0.61) | CDK1CDK2CCNB1CCNE1CDK9 | |
| SCHEMBL25468187 | 0.81 | CDK2 (0.41) | CDK1CDK2CCNB1CCNE1KDM4E | |
| SCHEMBL24767728 | 0.80 | MEN1 (0.55) | CDK1CDK2CCNB1CCNE1KDM4E | |
| SCHEMBL754057 | 0.80 | CDK2 (0.47) | CDK1CDK2CCNB1CCNE1KDM4E | |
| SCHEMBL15763710 | 0.79 | CDK5 (0.48) | CDK1CDK2CCNB1CCNE1KDM4E | |
| SCHEMBL22326763 | 0.79 | PDE2A (0.48) | CDK1CDK2CCNB1CCNE1CDK9 | |
| SCHEMBL21168954 | 0.79 | CDK5 (0.52) | KDM4ECDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11725024-B2 | Antibody drug conjugates | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-08-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11725024-B2 | Antibody drug conjugates | STING1, CGAS, TBK1 | CDK1 4505/4885CDK2 4781/4885CCNB1 4775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.