Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 5/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 5/20 | 0.46 |
| ▸ | AKR1C4 | P17516 | 3/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | ATIC | P31939 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPRA | P18433 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | PTPRE | P23469 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11302359 | 0.89 | TTR (0.41) | AKR1C2AKR1C1AKR1C4AKR1C3TP53 | |
| SCHEMBL8285522 | 0.88 | SELL (0.46) | AKR1C2AKR1C1AKR1C4AKR1C3TP53 | |
| SCHEMBL29396210 | 0.88 | TTR (0.56) | AKR1C2AKR1C1AKR1C4AKR1C3TP53 | |
| SCHEMBL425350 | 0.88 | TTR (0.56) | AKR1C2AKR1C1AKR1C4AKR1C3TP53 | |
| SCHEMBL23803707 | 0.86 | TTR (0.54) | AKR1C2AKR1C1AKR1C4AKR1C3TP53 | |
| SCHEMBL340511 | 0.86 | TTR (0.54) | AKR1C2AKR1C1AKR1C4AKR1C3TP53 | |
| Lithium SCHEMBL410866 | 0.86 | TTR (0.54) | AKR1C2AKR1C1AKR1C4AKR1C3TP53 | |
| SCHEMBL9398438 | 0.86 | TTR (0.54) | AKR1C2AKR1C1AKR1C4AKR1C3TP53 | |
| SCHEMBL9403722 | 0.86 | TTR (0.54) | AKR1C2AKR1C1AKR1C4AKR1C3TP53 | |
| Lithium SCHEMBL30311136 | 0.86 | TTR (0.54) | AKR1C2AKR1C1AKR1C4AKR1C3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150197-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |