Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 7/20 | 0.62 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | USP2 | O75604 | 3/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | BLM | P54132 | 3/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.62 |
| ▸ | RECQL | P46063 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.62 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | RGS12 | O14924 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8540405 | 0.83 | KDM4E (0.66) | THRBLMNAKDM4EKMT2AUSP2 | |
| SCHEMBL5286425 | 0.83 | KDM4E (0.66) | THRBLMNAKDM4EKMT2AUSP2 | |
| SCHEMBL25177946 | 0.82 | USP2 (0.47) | THRBLMNAKDM4EKMT2AUSP2 | |
| SCHEMBL25185929 | 0.82 | USP2 (0.47) | THRBLMNAKDM4EKMT2AUSP2 | |
| SCHEMBL25264034 | 0.82 | USP2 (0.47) | THRBLMNAKDM4EKMT2AUSP2 | |
| SCHEMBL25173130 | 0.82 | KDM4E (0.51) | THRBLMNAKDM4EKMT2AUSP2 | |
| SCHEMBL25186419 | 0.82 | KDM4E (0.47) | THRBLMNAKDM4EKMT2AUSP2 | |
| SCHEMBL25264658 | 0.82 | KDM4E (0.47) | THRBLMNAKDM4EKMT2AUSP2 | |
| SCHEMBL25173129 | 0.82 | KDM4E (0.51) | THRBLMNAKDM4EKMT2AUSP2 | |
| SCHEMBL25177948 | 0.82 | USP2 (0.47) | THRBLMNAKDM4EKMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150197-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |