Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | USP2 | O75604 | 3/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | BLM | P54132 | 3/20 | 0.66 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | RECQL | P46063 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | PKM | P14618 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.66 |
| ▸ | RGS12 | O14924 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5286425 | 1.00 | KDM4E (0.66) | KDM4EUSP2ALOX15HSD17B10LMNA | |
| Water SCHEMBL11769068 | 0.98 | KDM4E (0.64) | KDM4EUSP2ALOX15HSD17B10LMNA | |
| Water SCHEMBL11769062 | 0.98 | KDM4E (0.64) | KDM4EUSP2ALOX15HSD17B10LMNA | |
| SCHEMBL2679928 | 0.86 | KDM4E (0.66) | KDM4EUSP2ALOX15HSD17B10LMNA | |
| SCHEMBL4140820 | 0.86 | KDM4E (0.66) | KDM4EUSP2ALOX15HSD17B10LMNA | |
| SCHEMBL17774756 | 0.84 | KDM4E (0.64) | KDM4EUSP2ALOX15HSD17B10LMNA | |
| SCHEMBL17979624 | 0.83 | KDM4E (0.78) | KDM4EUSP2ALOX15HSD17B10LMNA | |
| SCHEMBL491072 | 0.83 | EGFR (0.47) | KDM4EUSP2ALOX15HSD17B10LMNA | |
| SCHEMBL19501942 | 0.83 | ALOX15 (0.57) | KDM4EUSP2ALOX15HSD17B10LMNA | |
| SCHEMBL5324787 | 0.83 | KDM4E (0.55) | KDM4EUSP2ALOX15HSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976782-A | 3-(2,5-Dihydroxyphenyl)-alanine as a cardiac stimulant | MERCK & CO., INC. (US) | 1976-08-24 | — | — | US | claimed |
| EP-0668874-B1 | LHRH ANTAGONISTS AND INTERMEDIATE PRODUCTS | SCHERING AG (DE) | 1998-08-26 | — | — | EP | disclosed |
| EP-0668874-A1 | LHRH ANTAGONISTS AND INTERMEDIATE PRODUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1995-08-30 | — | — | EP | disclosed |
| WO-1992020711-A2 | LHRH ANTAGONISTS AND INTERMEDIATE PRODUCTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-11-26 | — | — | WO | disclosed |
| US-3976782-A | 3-(2,5-Dihydroxyphenyl)-alanine as a cardiac stimulant | MERCK & CO., INC. (US) | 1976-08-24 | — | — | US | disclosed |
| US-3976782-A | 3-(2,5-Dihydroxyphenyl)-alanine as a cardiac stimulant | MERCK & CO., INC. (US) | 1976-08-24 | — | — | US | disclosed |
| US-3976782-A | 3-(2,5-Dihydroxyphenyl)-alanine as a cardiac stimulant | MERCK & CO., INC. (US) | 1976-08-24 | — | — | US | disclosed |