Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 4/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.49 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.49 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.49 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.49 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.49 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.49 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.49 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.49 |
| ▸ | CYP4F8 | P98187 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10424476 | 0.83 | MEN1 (0.39) | CYP1A1CYP1B1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29589241 | 0.80 | CYP1A1 (0.69) | CYP1A1CYP1B1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL196689 | 0.80 | CYP1A1 (0.69) | CYP1A1CYP1B1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL743497 | 0.78 | CA12 (0.43) | CYP1A1CYP1B1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2373679 | 0.78 | CYP1A1 (0.46) | CYP1A1CYP1B1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2598021 | 0.73 | CYP1A1 (0.49) | CYP1A1CYP1B1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11116451 | 0.73 | CYP1A1 (0.49) | CYP1A1CYP1B1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7459961 | 0.72 | BACE1 (0.44) | CYP1A1CYP1B1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11523594 | 0.72 | CYP1A1 (0.51) | CYP1A1CYP1B1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9411714 | 0.72 | CYP1A1 (0.41) | CYP1A1CYP1B1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011146791-A1 | ATYPICAL KESTERITE COMPOSITIONS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-11-24 | — | — | WO | disclosed |
| EP-0796250-A1 | PYRIDAZINONES AS ENDOTHELIN-RECEPTOR ANTAGONISTS | MERCK PATENT GmbH (DE) | 1997-09-24 | — | — | EP | disclosed |
| WO-1997013758-A1 | PYRIDAZINONES AS ENDOTHELIN-RECEPTOR ANTAGONISTS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1997-04-17 | — | — | WO | disclosed |
| EP-0342152-A2 | Mass-dyed highly molecular organic materials containing metal complexes; metal complexes and process for their preparation | CIBA-GEIGY AG (CH) | 1989-11-15 | — | — | EP | disclosed |
| EP-0036387-B1 | PROCESS FOR THE PREPARATION OF HYDRAZONO-ISOINDOLINES | CIBA-GEIGY AG (CH) | 1986-01-22 | — | — | EP | disclosed |
| US-4496727-A | ORGANIC PIGMENTS; PLASTICS; LACQUERS; INKS; COATINGS; COLOR FASTNESS | CIBA-GEIGY CORPORATION (US) | 1985-01-29 | — | — | US | disclosed |
| EP-0036834-B1 | PROCESS FOR THE PREPARATION OF METAL COMPLEXES OF ISOINDOLINE AZINES | CIBA-GEIGY AG (CH) | 1983-12-07 | — | — | EP | disclosed |
| US-4414395-A | REACTING AN IMINOISOINDOLE WITH HYDRAZINE | CIBA-GEIGY CORPORATION (US) | 1983-11-08 | — | — | US | disclosed |
| US-4385174-A | FOR PIGMENTS | CIBA-GEIGY CORPORATION (US) | 1983-05-24 | — | — | US | disclosed |
| EP-0036834-A1 | Process for the preparation of metal complexes of isoindoline azines | CIBA-GEIGY AG (CH) | 1981-09-30 | — | — | EP | disclosed |
| EP-0036387-A2 | Process for the preparation of hydrazono-isoindolines | CIBA-GEIGY AG (CH) | 1981-09-23 | — | — | EP | disclosed |
| EP-0036388-A2 | Isoindoline derivatives, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1981-09-23 | — | — | EP | disclosed |