Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | USP8 | P40818 | 3/20 | 0.39 |
| ▸ | USP7 | Q93009 | 3/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21876181 | 1.00 | HPGD (0.39) | HPGDKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL21876180 | 1.00 | HPGD (0.39) | HPGDKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL29372186 | 1.00 | HPGD (0.39) | HPGDKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL21876169 | 0.82 | KDM4E (0.40) | HPGDKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL21876170 | 0.82 | KDM4E (0.40) | HPGDKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL21834208 | 0.81 | PDE4A (0.35) | HPGDKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL21834207 | 0.81 | PDE4A (0.35) | HPGDKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL21876219 | 0.71 | ALDH1A1 (0.45) | KDM4EALDH1A1PDE4DIMPDH2IMPDH1 | |
| SCHEMBL21876221 | 0.71 | ALDH1A1 (0.45) | KDM4EALDH1A1PDE4DIMPDH2IMPDH1 | |
| SCHEMBL29372177 | 0.71 | ALDH1A1 (0.45) | KDM4EALDH1A1PDE4DIMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3596053-B1 | FARNESOID X RECEPTOR AGONISTS AND USES THEREOF | ORGANOVO INC (US) | 2023-08-16 | — | — | EP | disclosed |