SCHEMBL25980389

SCHEMBL25980389

O=C(CCOCCOCCC(=O)Oc1c(F)c(F)c(F)c(F)c1F)NC(COCCOCCOCCn1cc(CCOC[C@H]2C[C@@H](O)C[C@@H](O)[C@H]2O)nn1)COCCOCCOCCn1cc(CCOC[C@H]2C[C@@H](O)C[C@@H](O)[C@H]2O)nn1

nearest known ligand 0.31

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.31
DRD4 P21917 2/20 0.31
DRD3 P35462 2/20 0.31
MMP2 P08253 2/20 0.31
MMP9 P14780 2/20 0.31
MMP8 P22894 2/20 0.31
MMP13 P45452 2/20 0.31
LGALS3 P17931 1/20 0.31
FOLH1 Q04609 2/20 0.31
GLA P06280 2/20 0.31
GBA1 P04062 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25976050 0.89 LGALS3 (0.38) DRD2DRD4DRD3LGALS3
SCHEMBL25979356 0.85 LGALS3 (0.35) DRD2DRD4DRD3LGALS3
SCHEMBL25523095 0.81 LGALS3 (0.40) LGALS3
SCHEMBL25496656 0.81 LGALS3 (0.43) LGALS3FOLH1
SCHEMBL25980406 0.80 GLA (0.35) GLAGBA1
SCHEMBL25907004 0.80 LGALS3 (0.30) LGALS3
SCHEMBL25974686 0.79 LGALS3 (0.35) LGALS3
SCHEMBL25982998 0.78 LGALS3 (0.38) DRD2DRD4DRD3LGALS3
SCHEMBL25495212 0.78 LGALS3 (0.41) LGALS3
SCHEMBL25979345 0.78 LGALS3 (0.35) DRD2DRD4DRD3LGALS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. 2023-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250091-A1 ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES ASGR1, LAMP2, FCGR2A DRD2 3308/4885DRD4 3995/4885DRD3 3554/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.