⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25917209 | 0.78 | — | — | |
| SCHEMBL24895910 | 0.78 | — | — | |
| SCHEMBL15998504 | 0.78 | — | — | |
| SCHEMBL5690874 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL22852655 | 0.74 | — | — | |
| SCHEMBL24895974 | 0.72 | — | — | |
| SCHEMBL1513006 | 0.71 | — | — | |
| SCHEMBL25075845 | 0.71 | — | — | |
| SCHEMBL15359943 | 0.71 | — | — | |
| SCHEMBL19749040 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11939340-B2 | CDK inhibitors and their use as pharmaceuticals | PRELUDE THERAPEUTICS INCORPORATED (US) | 2024-03-26 | — | — | US | disclosed |
| US-20230234964-A1 | CDK Inhibitors And Their Use As Pharmaceuticals | PRELUDE THERAPEUTICS, INCORPORATED | 2023-07-27 | — | — | US | disclosed |