Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165870 | 0.72 | — | — | |
| SCHEMBL14290157 | 0.69 | CCR5 (0.42) | CCR5 | |
| SCHEMBL2598183 | 0.68 | — | — | |
| SCHEMBL1725268 | 0.68 | — | — | |
| Bromide SCHEMBL8698946 | 0.67 | — | — | |
| SCHEMBL7383342 | 0.62 | — | — | |
| SCHEMBL8147763 | 0.61 | — | — | |
| SCHEMBL19388090 | 0.60 | — | — | |
| SCHEMBL10398361 | 0.59 | CCR5 (0.33) | CCR5 | |
| SCHEMBL6263752 | 0.59 | EPAS1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571353-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | AbbVie Inc. (US) | 2013-03-27 | — | — | EP | claimed |
| WO-2011146089-A1 | MODULATORS OF 5-HT RECEPTORS AND METHODS OF USE THEREOF | ABBOTT LABORATORIES (US) | 2011-11-24 | — | — | WO | claimed |