Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31212333 | 1.00 | ATM (0.43) | ATMALDH1A1IDO1TDO2MAPT | |
| SCHEMBL28815005 | 0.77 | GAA (0.41) | IDO1TDO2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL7460748 | 0.66 | ATM (0.47) | ATMALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL7460745 | 0.66 | ATM (0.47) | ATMALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL14831119 | 0.65 | AKR1C3 (0.52) | ATMALDH1A1MAPTPKMNPSR1 | |
| SCHEMBL10281223 | 0.65 | KDM1A (0.34) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL5741892 | 0.63 | AKR1B1 (0.48) | MAPTKDM4EHPGDTDP1LMNA | |
| SCHEMBL8017835 | 0.62 | TSHR (0.48) | ATMALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL8017837 | 0.62 | TSHR (0.48) | ATMALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL27738180 | 0.62 | KMT2A (0.54) | MAPTSMN1; SMN2NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150663-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | RETUNE PHARMA INC. (US) | 2023-08-10 | — | — | WO | disclosed |