Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 5/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2784971 | 0.83 | GAA (0.46) | GAAESR1ESR2NOS3NOS1 | |
| SCHEMBL31212333 | 0.77 | ATM (0.43) | GAAIDO1TDO2NPC1RAB9A | |
| SCHEMBL25981306 | 0.77 | ATM (0.43) | GAAIDO1TDO2NPC1RAB9A | |
| SCHEMBL29220708 | 0.75 | GAA (0.46) | GAAESR1ESR2NPC1RAB9A | |
| SCHEMBL14833836 | 0.74 | CTSL (0.47) | CTSLNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL14833839 | 0.74 | CTSL (0.47) | CTSLNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL25876652 | 0.72 | NOS3 (0.37) | GAAESR1ESR2NOS3NOS1 | |
| SCHEMBL12479044 | 0.72 | RXRA (0.37) | GAAESR1ESR2 | |
| SCHEMBL24536162 | 0.71 | GAA (0.38) | GAAESR1ESR2 | |
| SCHEMBL1494661 | 0.71 | ESR1 (0.39) | GAAESR1ESR2CTSLIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114891070-A | Anthelmintic depsipeptide compounds | 勃林格殷格翰动物保健美国公司 | 2022-08-12 | — | — | CN | disclosed |
| CN-107835818-B | Anthelmintic depsipeptide compounds | 勃林格殷格翰动物保健美国公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-107835818-A | Anthelmintic depsipeptide compounds | 梅里亚股份有限公司 | 2018-03-23 | — | — | CN | disclosed |