SCHEMBL2598286

SCHEMBL2598286

CC(=CO)C(=O)OC(C)C

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.48
HCAR2 Q8TDS4 1/20 0.38
ADRA1A P35348 1/20 0.38
PDE4D Q08499 1/20 0.38
GAA P10253 2/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CA12 O43570 3/20 0.30
CA1 P00915 3/20 0.30
CA2 P00918 3/20 0.30
CA7 P43166 3/20 0.30
CA9 Q16790 3/20 0.30
CA14 Q9ULX7 3/20 0.30
LMNA P02545 2/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1532594 0.82 TSHR (0.50) TSHRHCAR2ADRA1APDE4DGAA
SCHEMBL13613127 0.82 TSHR (0.50) TSHRHCAR2ADRA1APDE4DGAA
SCHEMBL666918 0.82 TSHR (0.50) TSHRHCAR2ADRA1APDE4DGAA
SCHEMBL3338061 0.80 TSHR (0.48) TSHRHCAR2ADRA1APDE4DGAA
SCHEMBL448478 0.80 TSHR (0.48) TSHRHCAR2ADRA1APDE4DGAA
SCHEMBL10687993 0.80 TSHR (0.48) TSHRHCAR2ADRA1APDE4DGAA
SCHEMBL27539999 0.79 ALDH1A1 (0.32) TSHRALDH1A1
SCHEMBL28569998 0.78 TSHR (0.46) TSHRHCAR2ADRA1APDE4DGAA
SCHEMBL28790909 0.78 TSHR (0.46) TSHRHCAR2ADRA1APDE4DGAA
SCHEMBL2065903 0.78 TSHR (0.46) TSHRHCAR2ADRA1APDE4DGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150175836-A1 LOW BAKE TEMPERATURE CURABLE COATING COMPOSITIONS AND PROCESSES FOR PRODUCING COATINGS AT LOW BAKE TEMPERATURES BARCLAYS BANK PLC, AS COLLATERAL AGENT 2015-06-25 US claimed
CN-1246629-A Method for preparing colorful contact lens XINTAI SCIENCE AND TECHNOLOGY (CN) 2000-03-08 CN claimed
EP-0369581-A1 Temporary protective aqueous coating composition IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-05-23 EP claimed
US-4529777-A Crosslinking DAIDONE PHILIP 1985-07-16 US claimed
US-20240030550-A1 COPOLYMER FOR SEPARATOR, AND SECONDARY BATTERY COMPRISING SAME HANSOL CHEMICAL CO., LTD (KR) 2024-01-25 US disclosed
EP-4306608-A2 PRESSURE SENSITIVE ADHESIVES AND ARTICLES WITH HYPERBRANCHED SILSESQUIOXANE CORE AND METHODS OF MAKING THE SAME Avery Dennison Corporation (US) 2024-01-17 EP disclosed
EP-4303283-A2 PRESSURE SENSITIVE ADHESIVES AND ARTICLES WITH HYPERBRANCHED SILSESQUIOXANE CORE AND METHODS OF MAKING THE SAME Avery Dennison Corporation (US) 2024-01-10 EP disclosed
EP-3658643-B1 PRESSURE SENSITIVE ADHESIVES AND ARTICLES WITH HYPERBRANCHED SILSESQUIOXANE CORE AND METHODS OF MAKING THE SAME AVERY DENNISON CORP (US) 2024-01-03 EP disclosed
EP-4242241-A1 COPOLYMER FOR SEPARATOR, AND SECONDARY BATTERY COMPRISING SAME Hansol Chemical Co., Ltd (KR) 2023-09-13 EP disclosed
US-20230220249-A1 Pressure Sensitive Adhesives and Articles with Hyperbranched Silsesquioxane Core and Methods of Making the Same AVERY DENNISON CORP (US) 2023-07-13 US disclosed
US-11661533-B2 Pressure sensitive adhesives and articles with hyperbranched silsesquioxane core and methods of making the same AVERY DENNISON CORPORATION (US) 2023-05-30 US disclosed
US-20230159796-A1 Post-Polymerization Functionalization of Pendant Functional Groups AVERY DENNISON CORPORATION 2023-05-25 US disclosed
US-4373054-A POLYMERS FOR CATHODIC ELECTRODEPOSITION DULUX AUSTRALIA LTD. (AU) 1983-02-08 US disclosed
EP-0069582-A1 Polymer dispersions and their use in coating compositions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-01-12 EP disclosed
EP-0055270-A4 DISPERSION PROCESS AND PRODUCT. DULUX AUSTRALIA LTD (AU) 1982-11-17 EP disclosed
EP-0055270-A1 DISPERSION PROCESS AND PRODUCT. DULUX AUSTRALIA LTD (AU) 1982-07-07 EP disclosed
WO-1982000148-A1 DISPERSION PROCESS AND PRODUCT DULUX AUSTRALIA LTD (AU) 1982-01-21 WO disclosed
US-4233396-A Shaped polymeric articles made by two-stage photopolymerization IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1980-11-11 US disclosed
US-4165418-A PIGMENT DISPERSANT POLYMER CONTAINING HYDROXY, AMIDE AND ESTERIFIED EPOXIDE GROUPS IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-08-21 US disclosed
US-3941858-A DENTURE LINER, ACRYLATE POLYMER NATIONAL PATENT DEVELOPMENT CORPORATION (US) 1976-03-02 US disclosed