Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16617838 | 0.82 | CPB1 (0.47) | CPB1TSHRALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL16617836 | 0.82 | CPB1 (0.47) | CPB1TSHRALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL12282055 | 0.82 | CPB1 (0.57) | CPB1TSHRALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL19884365 | 0.82 | CPB1 (0.57) | CPB1TSHRALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL14202360 | 0.81 | CPB1 (0.51) | CPB1TSHRALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL17947657 | 0.80 | CPB1 (0.61) | CPB1TSHRALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL16617669 | 0.78 | CPB1 (0.57) | CPB1TSHRALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL16617667 | 0.78 | CPB1 (0.57) | CPB1TSHRALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL11904931 | 0.78 | CPB1 (0.57) | CPB1TSHRALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL16618141 | 0.77 | CPB1 (0.56) | CPB1TSHRALDH1A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3870578-B1 | THERAPEUTIC COMPOUNDS | C4X DISCOVERY LTD (GB) | 2023-08-16 | — | — | EP | disclosed |