Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | ALPL | P05186 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ADCY1 | Q08828 | 12/20 | 0.60 |
| ▸ | ADCY8 | P40145 | 11/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23188259 | 0.89 | ADCY1 (0.75) | ADCY1ADCY8HTR2B | |
| SCHEMBL25986184 | 0.85 | ADCY1 (0.52) | SLC2A1TP53ALOX15SMN1; SMN2KDM4E | |
| SCHEMBL25986311 | 0.85 | SLC2A1 (0.62) | SLC2A1TP53ALOX15SMN1; SMN2KDM4E | |
| SCHEMBL25986162 | 0.84 | SMN1; SMN2 (0.61) | SLC2A1TP53ALOX15SMN1; SMN2KDM4E | |
| SCHEMBL23160938 | 0.82 | ADCY1 (0.54) | SLC2A1TP53ALOX15SMN1; SMN2KDM4E | |
| SCHEMBL25986255 | 0.80 | ADCY1 (0.69) | ADCY1ADCY8HTR2B | |
| SCHEMBL25986208 | 0.80 | ADCY1 (0.70) | ADCY1ADCY8HTR2B | |
| SCHEMBL25986207 | 0.80 | ADCY1 (0.69) | ADCY1ADCY8HTR2B | |
| SCHEMBL25986210 | 0.80 | ADCY1 (0.64) | ADCY1ADCY8HTR2B | |
| SCHEMBL23188246 | 0.80 | ADCY1 (0.69) | ADCY1ADCY8HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230250084-A1 | PYRAZOLYL PYRIMIDINONE COMPOUNDS AND THE USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2023-08-10 | — | — | US | disclosed |
| US-20230250084-A1 | PYRAZOLYL PYRIMIDINONE COMPOUNDS AND THE USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2023-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250084-A1 | PYRAZOLYL PYRIMIDINONE COMPOUNDS AND THE USES THEREOF | CAP1, ADCY1, ADCYAP1R1 | SLC2A1 4314/4885TP53 4807/4885ALOX15 359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.