SCHEMBL2598801

SCHEMBL2598801

CN1CCN(c2ccc3nnn(Cc4ccc5ncccc5c4)c3n2)CC1.OC1CCN(c2ccc3nnn(Cc4ccc5ncccc5c4)c3n2)C1

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MET P08581 19/20 0.73
CHKA P35790 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2598802 1.00 MET (0.73) METCHKA
SCHEMBL1330874 0.94 MET (0.78) MET
SCHEMBL1330869 0.94 MET (0.78) MET
SCHEMBL1330803 0.90 MET (0.78) METCHKA
SCHEMBL2571830 0.84 MET (1.00) MET
SCHEMBL2572822 0.84 MET (1.00) MET
SCHEMBL2588320 0.84 MET (1.00) MET
SCHEMBL12489710 0.83 MET (0.60) MET
SCHEMBL15294695 0.81 MET (0.63) MET
SCHEMBL2572252 0.81 MET (0.90) MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2571878-A1 NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B]PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES Incozen Therapeutics Pvt. Ltd. (IN) 2013-03-27 EP claimed
WO-2011145035-A1 NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B] PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES INDIAN INCOZEN THERAPEUTICS PVT. LTD. (IN) 2011-11-24 WO claimed