SCHEMBL25988051

SCHEMBL25988051

CNC(CCCCNC(=O)OCc1ccccc1)C(=O)I

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 3/20 0.60
▸ MMP2 P08253 2/20 0.57
▸ MMP9 P14780 2/20 0.57
▸ HTT P42858 1/20 0.56
▸ SIRT5 Q9NXA8 1/20 0.55
▸ SIRT2 Q8IXJ6 2/20 0.54
▸ SIRT1 Q96EB6 2/20 0.54
▸ CA1 P00915 1/20 0.54
▸ CA2 P00918 1/20 0.54
▸ TGM2 P21980 1/20 0.54
▸ SIRT3 Q9NTG7 1/20 0.53
▸ CPB1 P15086 1/20 0.53
▸ CPB2 Q96IY4 1/20 0.53
▸ DPP8 Q6V1X1 1/20 0.53
▸ DPP7 Q9UHL4 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13227705 0.90 FOLH1 (0.69) FOLH1MMP2MMP9HTTSIRT2
SCHEMBL31265517 0.90 FOLH1 (0.69) FOLH1MMP2MMP9HTTSIRT2
SCHEMBL31265519 0.90 FOLH1 (0.69) FOLH1MMP2MMP9HTTSIRT2
SCHEMBL22674651 0.88 FOLH1 (0.60) FOLH1MMP2MMP9HTTSIRT2
SCHEMBL25455599 0.86 HTT (0.60) FOLH1MMP2MMP9HTTCA1
SCHEMBL17995299 0.86 FOLH1 (0.64) FOLH1MMP2MMP9HTTSIRT2
SCHEMBL14719981 0.85 MAPT (0.61) FOLH1MMP2MMP9HTT
SCHEMBL14719982 0.85 MAPT (0.61) FOLH1MMP2MMP9HTT
SCHEMBL30958397 0.83 FOLH1 (0.61) FOLH1MMP2MMP9HTTSIRT2
SCHEMBL13251388 0.82 HTT (0.65) FOLH1MMP2MMP9HTTTGM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218042-A1 MODIFIED LIPIDATED RELAXIN B CHAIN PEPTIDES AND THEIR THERAPEUTIC USE SANOFI (FR) 2024-07-04 — — US disclosed
US-11725036-B2 Modified lipidated relaxin B chain peptides and their therapeutic use SANOFI (FR) 2023-08-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240218042-A1 MODIFIED LIPIDATED RELAXIN B CHAIN PEPTIDES AND THEIR THERAPEUTIC USE RXFP1, RXFP2, RXFP4 FOLH1 2255/4885MMP2 2377/4885MMP9 1927/4885
US-11725036-B2 Modified lipidated relaxin B chain peptides and their therapeutic use SCTR, RXFP1, RXFP3 FOLH1 683/4885MMP2 2674/4885MMP9 2804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback