Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 12/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29561663 | 0.86 | MAPT (0.42) | GPR52NPC1RAB9ATDP1ALDH1A1 | |
| SCHEMBL30573 | 0.86 | MAPT (0.42) | GPR52NPC1RAB9ATDP1ALDH1A1 | |
| SCHEMBL28251467 | 0.86 | MAPT (0.42) | GPR52NPC1RAB9ATDP1ALDH1A1 | |
| Methane SCHEMBL28134892 | 0.85 | MAPT (0.41) | GPR52NPC1RAB9ATDP1ALDH1A1 | |
| SCHEMBL22720628 | 0.85 | MAPT (0.41) | GPR52NPC1RAB9ATDP1ALDH1A1 | |
| Bicarbonate SCHEMBL28901195 | 0.85 | MAPT (0.41) | GPR52NPC1RAB9ATDP1ALDH1A1 | |
| SCHEMBL11851207 | 0.85 | MAPT (0.41) | GPR52NPC1RAB9ATDP1ALDH1A1 | |
| SCHEMBL27540791 | 0.85 | MAPT (0.41) | GPR52NPC1RAB9ATDP1ALDH1A1 | |
| Phloretin SCHEMBL1260339 | 0.84 | SLC5A1 (0.51) | TDP1ALDH1A1HPGDMEN1CYP1A2 | |
| Alcohol SCHEMBL11308930 | 0.83 | AKT1 (0.39) | GPR52NPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011144579-A1 | IMPROVED PREPARATION OF CHALCONE DERIVATIVES | GENFIT (FR) | 2011-11-24 | — | — | WO | disclosed |