Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1331353 | 0.92 | MET (0.68) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL1331578 | 0.81 | MET (0.70) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL1330784 | 0.78 | MET (0.79) | MET | |
| SCHEMBL1329543 | 0.78 | MET (0.78) | MET | |
| SCHEMBL2570437 | 0.77 | MET (0.68) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL12122110 | 0.75 | MET (0.66) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL21172008 | 0.75 | MET (0.61) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL1329272 | 0.74 | MET (0.56) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL1330543 | 0.74 | MET (0.56) | METCYP2C9PDE3BPDE3APDE10A | |
| SCHEMBL1330120 | 0.74 | MET (0.80) | METCYP2C9PDE3BPDE3APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011145035-A1 | NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B] PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES | INDIAN INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-11-24 | — | — | WO | claimed |