Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 3/20 | 0.38 |
| ▸ | SORD | Q00796 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 6/20 | 0.32 |
| ▸ | KHK | P50053 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | RAF1 | P04049 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22828722 | 0.89 | RBP4 (0.35) | RBP4SORDKHKMAPK1MEN1 | |
| SCHEMBL22828262 | 0.86 | RBP4 (0.39) | RBP4SORDHPGDTTRIDH2 | |
| SCHEMBL22828474 | 0.85 | RBP4 (0.35) | RBP4KHK | |
| SCHEMBL25990425 | 0.82 | KHK (0.33) | RBP4IDH2KHK | |
| SCHEMBL22828723 | 0.78 | KHK (0.39) | RBP4SORDHPGDKHKMAPK1 | |
| SCHEMBL25990342 | 0.78 | HDAC4 (0.41) | IDH2 | |
| SCHEMBL22828720 | 0.73 | CYP1A2 (0.38) | SORDHPGDKHKMAPK1HSD17B10 | |
| SCHEMBL22828654 | 0.72 | MAPT (0.38) | HPGDIDH2KHKHSD17B10MEN1 | |
| SCHEMBL22828248 | 0.71 | KHK (0.36) | SORDHPGDKHKMAPK1HSD17B10 | |
| SCHEMBL25990778 | 0.71 | KHK (0.36) | SORDHPGDKHKMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3983404-B1 | DISUBSTITUTED PYRAZOLE COMPOUNDS AS KETOHEXOKINASE INHBITORS | LILLY CO ELI (US) | 2023-08-09 | — | — | EP | disclosed |