Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 11/20 | 0.45 |
| ▸ | KDR | P35968 | 9/20 | 0.42 |
| ▸ | CSF1R | P07333 | 8/20 | 0.42 |
| ▸ | KIT | P10721 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | NRAS | P01111 | 3/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24231379 | 1.00 | FLT3 (0.45) | FLT3KDRCSF1RKITCYP2D6 | |
| SCHEMBL24231319 | 0.92 | FLT3 (0.49) | FLT3KDRCSF1RKITCYP2D6 | |
| SCHEMBL25989698 | 0.92 | FLT3 (0.49) | FLT3KDRCSF1RKITCYP2D6 | |
| SCHEMBL24232004 | 0.89 | FLT3 (0.47) | FLT3KDRCSF1RKITCYP2D6 | |
| SCHEMBL24231298 | 0.89 | FLT3 (0.58) | FLT3KDRCSF1RKITCYP2D6 | |
| SCHEMBL25991404 | 0.89 | FLT3 (0.58) | FLT3KDRCSF1RKITCYP2D6 | |
| SCHEMBL26358053 | 0.89 | FLT3 (0.41) | FLT3KDRCSF1RKITCYP2D6 | |
| SCHEMBL25988834 | 0.87 | KDR (0.44) | FLT3KDRCSF1RKITCYP2D6 | |
| SCHEMBL30621279 | 0.86 | MAPK8 (0.48) | FLT3KDRCSF1RKITCYP2D6 | |
| SCHEMBL24975899 | 0.86 | MAPK8 (0.48) | FLT3KDRCSF1RKITCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150601-A2 | MULTI-CYCLIC IRAK AND FLT3 INHIBITING COMPOUNDS AND USES THEREOF | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2023-08-10 | — | — | WO | disclosed |