Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 20/20 | 0.48 |
| ▸ | CDKL5 | O76039 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1329700 | 0.98 | MET (0.49) | METCDKL5KCNH2 | |
| SCHEMBL1330789 | 0.95 | MET (0.50) | METCDKL5KCNH2 | |
| SCHEMBL1328740 | 0.92 | MET (0.49) | METCDKL5KCNH2 | |
| Hydrochloric Acid SCHEMBL1328996 | 0.92 | MET (0.48) | METCDKL5KCNH2 | |
| SCHEMBL1329016 | 0.91 | MET (0.51) | METCDKL5KCNH2 | |
| SCHEMBL1329316 | 0.91 | MET (0.56) | METCDKL5KCNH2 | |
| Hydrochloric Acid SCHEMBL1328897 | 0.91 | MET (0.50) | METCDKL5KCNH2 | |
| Hydrochloric Acid SCHEMBL1328425 | 0.90 | MET (0.55) | METCDKL5KCNH2 | |
| SCHEMBL1330056 | 0.90 | MET (0.49) | METCDKL5KCNH2 | |
| SCHEMBL1328885 | 0.89 | MET (0.61) | METCDKL5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571878-A1 | NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B]PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES | Incozen Therapeutics Pvt. Ltd. (IN) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011145035-A1 | NOVEL 3,5-DISUBSTITUED-3H-IMIDAZO[4,5-B]PYRIDINE AND 3,5- DISUBSTITUED -3H-[1,2,3]TRIAZOLO[4,5-B] PYRIDINE COMPOUNDS AS MODULATORS OF PROTEIN KINASES | INDIAN INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-11-24 | — | — | WO | disclosed |