Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 17/20 | 0.48 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2599663 | 1.00 | PIK3C3 (0.48) | PIK3C3PIK3CDPIK3CAATRMTOR | |
| SCHEMBL2599611 | 1.00 | PIK3C3 (0.48) | PIK3C3PIK3CDPIK3CAATRMTOR | |
| SCHEMBL24269719 | 0.84 | PIK3C3 (0.56) | PIK3C3 | |
| SCHEMBL26685798 | 0.84 | PIK3C3 (0.56) | PIK3C3 | |
| SCHEMBL16388496 | 0.82 | PIK3C3 (0.48) | PIK3C3PIK3CDPIK3CAATR | |
| SCHEMBL14087877 | 0.82 | PIK3C3 (0.48) | PIK3C3PIK3CAMTOR | |
| SCHEMBL14087747 | 0.82 | PIK3C3 (0.48) | PIK3C3PIK3CAMTOR | |
| SCHEMBL16388748 | 0.82 | PIK3C3 (0.48) | PIK3C3PIK3CDPIK3CAATR | |
| SCHEMBL19863417 | 0.81 | PIK3C3 (0.49) | PIK3C3 | |
| SCHEMBL16611301 | 0.81 | PIK3C3 (0.49) | PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571872-B1 | COMPOUNDS | TREHERNE JOHNATHAN MARK (GB) | 2014-12-31 | — | — | EP | disclosed |
| EP-2571872-B1 | COMPOUNDS | TREHERNE JOHNATHAN MARK (GB) | 2014-12-31 | — | — | EP | disclosed |
| EP-2571872-A1 | COMPOUNDS | BTG International Limited (GB) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011144578-A1 | COMPOUNDS | SENEXIS LIMITED (GB) | 2011-11-24 | — | — | WO | disclosed |
| WO-2011144578-A1 | COMPOUNDS | SENEXIS LIMITED (GB) | 2011-11-24 | — | — | WO | disclosed |