Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DCK | P27707 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL16332340 | 0.94 | CYP17A1 (0.36) | PIK3CDPIK3CBPIK3CGALDH1A1HSD17B10 | |
| SCHEMBL2599612 | 0.87 | PIK3CD (0.36) | PIK3CDPIK3CBPIK3CGALDH1A1HTR6 | |
| SCHEMBL2599637 | 0.86 | APP (0.41) | PIK3CDPIK3CBPIK3CGHTR6AVPR1A | |
| Dimethylamine SCHEMBL2599639 | 0.86 | CYP17A1 (0.40) | PIK3CDPIK3CBPIK3CGALDH1A1KMT2A | |
| SCHEMBL2599603 | 0.85 | MAPT (0.40) | PIK3CDPIK3CBPIK3CGKMT2ATSHR | |
| SCHEMBL2599623 | 0.84 | DHFR (0.40) | ALDH1A1HSD17B10KDM4EKMT2AHTR6 | |
| SCHEMBL16388793 | 0.82 | PIK3CA (0.37) | PIK3CDPIK3CBPIK3CGAVPR1ACYP1A2 | |
| SCHEMBL2599667 | 0.82 | AVPR1A (0.35) | PIK3CDPIK3CBPIK3CGHTR6AVPR1A | |
| SCHEMBL16332713 | 0.81 | CYP17A1 (0.34) | PIK3CDPIK3CBPIK3CGHTR6AVPR1A | |
| SCHEMBL16388603 | 0.80 | F10 (0.37) | PIK3CDPIK3CBPIK3CGAVPR1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571872-B1 | COMPOUNDS | TREHERNE JOHNATHAN MARK (GB) | 2014-12-31 | — | — | EP | claimed |
| EP-2571872-A1 | COMPOUNDS | BTG International Limited (GB) | 2013-03-27 | — | — | EP | claimed |
| WO-2011144578-A1 | COMPOUNDS | SENEXIS LIMITED (GB) | 2011-11-24 | — | — | WO | claimed |
| EP-2571872-B1 | COMPOUNDS | TREHERNE JOHNATHAN MARK (GB) | 2014-12-31 | — | — | EP | disclosed |
| EP-2571872-B1 | COMPOUNDS | TREHERNE JOHNATHAN MARK (GB) | 2014-12-31 | — | — | EP | disclosed |
| EP-2571872-A1 | COMPOUNDS | BTG International Limited (GB) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011144578-A1 | COMPOUNDS | SENEXIS LIMITED (GB) | 2011-11-24 | — | — | WO | disclosed |