Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16961115 | 0.78 | ALOX5AP (0.36) | HTR2C | |
| SCHEMBL671184 | 0.77 | FFAR4 (0.34) | HTR2CFFAR4 | |
| SCHEMBL16954185 | 0.75 | MGLL (0.40) | FFAR4 | |
| SCHEMBL2599724 | 0.72 | ESR2 (0.33) | — | |
| SCHEMBL16960072 | 0.72 | FFAR4 (0.42) | HTR2CFFAR4 | |
| SCHEMBL16957587 | 0.70 | FFAR4 (0.42) | HTR2CFFAR4 | |
| SCHEMBL14689866 | 0.68 | FFAR4 (0.32) | HTR2CFFAR4 | |
| SCHEMBL16954480 | 0.67 | ESR2 (0.40) | — | |
| SCHEMBL3908320 | 0.67 | EPHX1 (0.37) | HTR2C | |
| SCHEMBL16959404 | 0.66 | EPHX1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2571356-A1 | SPIRO ISOXAZOLINE COMPOUNDS AS SSTR5 ANTAGONISTS | Merck Sharp & Dohme Corp. (US) | 2013-03-27 | — | — | EP | disclosed |
| WO-2011146324-A1 | SPIRO ISOXAZOLINE COMPOUNDS AS SSTR5 ANTAGONISTS | MERCK SHARP & DOHME CORP. (US) | 2011-11-24 | — | — | WO | disclosed |