SCHEMBL25997236

SCHEMBL25997236

CC(=O)C1(CCCc2ccccc2CCCC2(C(=O)O)CC2)CC1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.34
KMT2A Q03164 5/20 0.34
MEN1 O00255 4/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
LMNA P02545 2/20 0.34
POLB P06746 1/20 0.34
PKM P14618 1/20 0.34
MAPT P10636 1/20 0.34
CYP4F2 P78329 1/20 0.33
CYP4A11 Q02928 1/20 0.33
CPB2 Q96IY4 2/20 0.33
MTNR1A P48039 2/20 0.33
MTNR1B P49286 1/20 0.33
NPY1R P25929 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26062066 0.95 CYP4F2 (0.35) ALDH1A1L3MBTL1CYP4F2CYP4A11MTNR1A
SCHEMBL25997246 0.94 BID (0.35) CYP4F2CYP4A11
SCHEMBL26062077 0.94 BID (0.35) CYP4F2CYP4A11
SCHEMBL26062074 0.94 BID (0.35) CYP4F2CYP4A11
SCHEMBL26062073 0.94 BID (0.35) CYP4F2CYP4A11
SCHEMBL25997249 0.94 BID (0.35) CYP4F2CYP4A11
SCHEMBL25997257 0.94 BID (0.35) CYP4F2CYP4A11
SCHEMBL25997242 0.94 CYP4F2 (0.36) ALDH1A1KMT2AMEN1L3MBTL1LMNA
SCHEMBL30549450 0.92 AKR1C1 (0.36) ALDH1A1KMT2AMEN1L3MBTL1LMNA
SCHEMBL22921430 0.92 AKR1C1 (0.36) ALDH1A1KMT2AMEN1L3MBTL1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11737995-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease ESPERVITA THERAPEUTICS, INC. (US) 2023-08-29 US disclosed
US-11730712-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease ESPERVITA THERAPEUTICS, INC. (US) 2023-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11737995-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease AHR, PKD1, CFTR ALDH1A1 202/4885KMT2A 1717/4885MEN1 3434/4885
US-11730712-B2 Functionalized long-chain hydrocarbon mono- and di-carboxylic acids and derivatives thereof, and their use for the prevention or treatment of disease CPT1A, PPARG, PC ALDH1A1 288/4885KMT2A 2272/4885MEN1 3931/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.