Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | DDO | Q99489 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30084670 | 0.80 | NQO2 (0.52) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL29386370 | 0.80 | NQO2 (0.52) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL25955236 | 0.77 | MEN1 (0.41) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL24663393 | 0.77 | DAO (0.39) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL24652317 | 0.77 | MEN1 (0.46) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL23053933 | 0.77 | ESR1 (0.39) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL25809892 | 0.77 | ALDH1A1 (0.39) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL24731143 | 0.74 | MEN1 (0.34) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL30075996 | 0.74 | PTGS1 (0.35) | MEN1KMT2AALDH1A1DNMT1CACNA1B | |
| SCHEMBL28889503 | 0.74 | PTGS1 (0.35) | MEN1KMT2AALDH1A1DNMT1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4223761-A1 | QUINAZOLINE COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-08-09 | — | — | EP | disclosed |