Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLB1 | P16278 | 1/20 | 0.54 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.54 |
| ▸ | CTRC | Q99895 | 1/20 | 0.54 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848405 | 0.82 | MAPT (0.47) | GLB1CTRB1CTRCMEN1KMT2A | |
| SCHEMBL11691771 | 0.82 | GLB1 (0.74) | GLB1CTRB1CTRCCYP1A1CYP1B1 | |
| SCHEMBL11809149 | 0.82 | GLB1 (0.74) | GLB1CTRB1CTRCCYP1A1CYP1B1 | |
| SCHEMBL9848426 | 0.82 | MAPT (0.47) | GLB1CTRB1CTRCMEN1KMT2A | |
| SCHEMBL11691780 | 0.82 | GLB1 (0.74) | GLB1CTRB1CTRCCYP1A1CYP1B1 | |
| SCHEMBL9848418 | 0.82 | MAPT (0.47) | GLB1CTRB1CTRCMEN1KMT2A | |
| SCHEMBL22604967 | 0.77 | MEN1 (0.36) | MEN1KMT2ANPC1RAB9ACASP3 | |
| SCHEMBL28661966 | 0.76 | GLB1 (0.58) | GLB1CTRB1CTRCCYP1A1CYP1B1 | |
| SCHEMBL16557818 | 0.72 | NPC1 (0.46) | MEN1KMT2ANPC1RAB9ASLC22A2 | |
| SCHEMBL17548221 | 0.72 | GLB1 (0.54) | GLB1CTRB1CTRCCYP1A1CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230265068-A1 | TRANSIENT RECEPTOR POTENTIAL CANONICAL 3 INHIBITORS AND METHODS OF USE THEREOF | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2023-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230265068-A1 | TRANSIENT RECEPTOR POTENTIAL CANONICAL 3 INHIBITORS AND METHODS OF USE THEREOF | TRPC3, TRPV3, TRPV1 | GLB1 3898/4885CTRB1 3388/4885CTRC 2560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.