SCHEMBL26005877

SCHEMBL26005877

c1ccc(-c2ccc(N(c3ccc(-c4ccc5c(ccc6ccccc65)c4)cc3)c3ccc(-c4ccc5c(ccc6cc(-c7ccc(-c8ccc(-c9ccc(N(c%10ccc%11c(ccc%12ccccc%12%11)c%10)c%10ccc%11c(ccc%12ccccc%12%11)c%10)cc9)cc8)cc7)ccc65)c4)cc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 2/20 0.44
CYP1B1 Q16678 2/20 0.44
HIF1A Q16665 1/20 0.44
ESR1 P03372 6/20 0.43
ESR2 Q92731 6/20 0.43
HPRT1 P00492 3/20 0.42
CYP2A6 P11509 1/20 0.40
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
BACE1 P56817 1/20 0.40
HSD17B1 P14061 3/20 0.40
HSD17B2 P37059 3/20 0.40
GPR84 Q9NQS5 1/20 0.39
CYP1A2 P05177 3/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2B6 P20813 1/20 0.39
CYP2C19 P33261 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20466428 1.00 ALDH1A1 (0.44) ALDH1A1HSD17B10CYP1B1HIF1AESR1
SCHEMBL20466443 1.00 ALDH1A1 (0.44) ALDH1A1HSD17B10CYP1B1HIF1AESR1
SCHEMBL20466432 0.97 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP1B1HIF1AESR1
SCHEMBL19598826 0.97 ALDH1A1 (0.47) ALDH1A1HSD17B10CYP1B1HIF1AESR1
SCHEMBL20466406 0.97 ALDH1A1 (0.47) ALDH1A1HSD17B10CYP1B1HIF1AESR1
SCHEMBL23471750 0.97 ALDH1A1 (0.47) ALDH1A1HSD17B10CYP1B1HIF1AESR1
SCHEMBL20466453 0.97 ALDH1A1 (0.47) ALDH1A1HSD17B10CYP1B1HIF1AESR1
SCHEMBL23154502 0.97 ALDH1A1 (0.47) ALDH1A1HSD17B10CYP1B1HIF1AESR1
SCHEMBL24372489 0.97 ALDH1A1 (0.47) ALDH1A1HSD17B10CYP1B1HIF1AESR1
SCHEMBL20466440 0.97 ALDH1A1 (0.47) ALDH1A1HSD17B10CYP1B1HIF1AESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210002-A1 COMPOSITION, AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-06-29 US disclosed