SCHEMBL26007451

SCHEMBL26007451

c1ccc(-c2nc(-c3cccc(-n4c5ccccc5c5ccc6ccccc6c54)c3)nc(-c3ccc4ccc5ccc6ccccc6c5c4c3)n2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
GAA P10253 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
PTGES O14684 1/20 0.32
PLA2G10 O15496 1/20 0.31
LMNA P02545 2/20 0.31
MAPT P10636 2/20 0.31
NPC1 O15118 1/20 0.31
RECQL P46063 1/20 0.31
RAB9A P51151 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ABCG2 Q9UNQ0 3/20 0.31
ALDH1A1 P00352 2/20 0.31
PDPK1 O15530 2/20 0.31
PTGER4 P35408 1/20 0.31
RXFP1 Q9HBX9 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26007457 0.96 PDPK1 (0.34) KDM4EATML3MBTL1GAAMEN1
SCHEMBL26007450 0.93 ATM (0.36) KDM4EATML3MBTL1MEN1KMT2A
SCHEMBL21207754 0.92 KDM4E (0.36) KDM4EATML3MBTL1GAAMEN1
SCHEMBL26012337 0.92 KDM4E (0.36) KDM4EATML3MBTL1GAAMEN1
SCHEMBL24152024 0.92 KDM4E (0.38) KDM4EATML3MBTL1GAAMEN1
SCHEMBL26006843 0.92 KDM4E (0.41) KDM4EATML3MBTL1GAAMEN1
SCHEMBL16726719 0.92 KDM4E (0.40) KDM4EATML3MBTL1GAAMEN1
SCHEMBL26007468 0.91 KDM4E (0.36) KDM4EATML3MBTL1GAAMEN1
SCHEMBL24152201 0.90 L3MBTL1 (0.41) KDM4EATML3MBTL1GAAMEN1
SCHEMBL24361337 0.90 KDM4E (0.36) KDM4EATML3MBTL1GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023146296-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-08-03 WO disclosed