Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20320735 | 0.85 | TRPM8 (0.51) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL20305318 | 0.85 | TRPM8 (0.51) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL20321010 | 0.82 | KDM4E (0.47) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL20321191 | 0.82 | KDM4E (0.47) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL20320995 | 0.82 | KDM4E (0.47) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL20305253 | 0.81 | IDO1 (0.40) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL20305360 | 0.81 | IDO1 (0.40) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL22374940 | 0.81 | IDO1 (0.40) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL20321090 | 0.81 | IDO1 (0.40) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL20320979 | 0.81 | IDO1 (0.40) | KDM4EMAPTDAOHPGDSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3557998-B1 | COMPOUNS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS INC (US) | 2023-08-16 | — | — | EP | disclosed |