Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL826568 | 0.85 | TDP1 (0.42) | L3MBTL1TDP1GAACTRCCYP2D6 | |
| SCHEMBL9587868 | 0.82 | TDP1 (0.46) | L3MBTL1TDP1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6170187 | 0.79 | — | — | |
| SCHEMBL18924363 | 0.78 | TDP1 (0.43) | L3MBTL1TDP1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL20643181 | 0.78 | CYP2D6 (0.46) | L3MBTL1TDP1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7253760 | 0.77 | L3MBTL1 (0.42) | L3MBTL1TDP1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL22511907 | 0.77 | TDP1 (0.42) | L3MBTL1TDP1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8765014 | 0.77 | L3MBTL1 (0.42) | L3MBTL1TDP1CTRCCYP2D6CYP2C9 | |
| SCHEMBL25774612 | 0.77 | TYR (0.52) | L3MBTL1TDP1CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL14157286 | 0.76 | TAAR1 (0.52) | GAACYP2A6AOC1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4048397-B1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THERAPEUTIC APPLICATIONS | UNIV MICHIGAN REGENTS (US) | 2023-08-16 | — | — | EP | disclosed |