SCHEMBL26017221

SCHEMBL26017221

Bc1c(B)c(B)c(-c2ccc3oc4c(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)cccc4c3c2)c(B)c1B

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.40
MAPT P10636 7/20 0.37
PTPRF P10586 5/20 0.36
PTPN2 P17706 5/20 0.36
PTPN1 P18031 5/20 0.36
ALDH1A1 P00352 5/20 0.36
KDM4E B2RXH2 4/20 0.36
HPGD P15428 4/20 0.36
POLB P06746 2/20 0.36
PIM1 P11309 1/20 0.36
CSNK2A2 P19784 1/20 0.36
CSNK2B P67870 1/20 0.36
PIM3 Q86V86 1/20 0.36
PIM2 Q9P1W9 1/20 0.36
TSHR P16473 4/20 0.36
HSD17B10 Q99714 3/20 0.36
ALOX15 P16050 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
NPSR1 Q6W5P4 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25632245 0.99 ALOX5 (0.39) ALOX5MAPTPTPRFPTPN2PTPN1
SCHEMBL26017463 0.98 ALOX5 (0.43) ALOX5MAPTPTPRFPTPN2PTPN1
SCHEMBL25632321 0.96 PIM1 (0.38) ALOX5MAPTPTPRFPTPN2PTPN1
SCHEMBL25632265 0.96 PIM1 (0.38) ALOX5MAPTPTPRFPTPN2PTPN1
SCHEMBL25631764 0.95 PIM1 (0.39) ALOX5MAPTPTPRFPTPN2PTPN1
SCHEMBL25632303 0.95 PIM1 (0.39) ALOX5MAPTPTPRFPTPN2PTPN1
SCHEMBL25653105 0.94 ALOX5 (0.40) ALOX5MAPTPTPRFPTPN2PTPN1
SCHEMBL26059756 0.94 ALOX5 (0.40) ALOX5MAPTPTPRFPTPN2PTPN1
SCHEMBL25638565 0.93 ALOX5 (0.41) ALOX5MAPTPTPRFPTPN2PTPN1
SCHEMBL25638889 0.93 ALOX5 (0.38) ALOX5MAPTPTPRFPTPN2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230263054-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-08-17 US disclosed