Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 11/20 | 0.48 |
| ▸ | DRD5 | P21918 | 11/20 | 0.48 |
| ▸ | DRD2 | P14416 | 10/20 | 0.48 |
| ▸ | DRD3 | P35462 | 10/20 | 0.48 |
| ▸ | DRD4 | P21917 | 5/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31354922 | 0.89 | DRD1 (0.51) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL25895602 | 0.89 | DRD1 (0.51) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL26838912 | 0.79 | DRD1 (0.49) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL26838844 | 0.78 | MAPKAPK2 (0.52) | CDK1MAPKAPK2CYP1A2CYP2D6ALOX15 | |
| SCHEMBL26838913 | 0.76 | DRD2 (0.46) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL31354914 | 0.75 | DRD2 (0.75) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL25895608 | 0.75 | DRD2 (0.75) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL31355006 | 0.73 | DRD2 (0.46) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL25895761 | 0.73 | DRD2 (0.46) | DRD1DRD5DRD2DRD3DRD4 | |
| SCHEMBL14438128 | 0.72 | CYP17A1 (0.47) | CYP17A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230382919-A1 | OXA- IBOGAINE INSPIRED ANALOGUES FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2023-11-30 | — | — | US | disclosed |
| WO-2023122135-A1 | SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME | KULEON LLC (US) | 2023-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230382919-A1 | OXA- IBOGAINE INSPIRED ANALOGUES FOR TREATMENT OF NEUROLOGICAL AND PSYCHIATRIC DISORDERS | GRIA4, GRIA3, GRIN3A | DRD1 109/4885DRD5 210/4885DRD2 80/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.