Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY1 | Q08828 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.58 |
| ▸ | HTT | P42858 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 5/20 | 0.52 |
| ▸ | USP2 | O75604 | 4/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21464953 | 0.88 | ADCY1 (0.78) | ADCY1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL20597939 | 0.75 | ADCY1 (1.00) | ADCY1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL21464807 | 0.75 | ADCY1 (0.71) | ADCY1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL21465001 | 0.73 | KDM4E (0.74) | ADCY1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL22594363 | 0.73 | KDM4E (0.71) | ADCY1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL22994218 | 0.72 | ADCY1 (0.70) | ADCY1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL22994222 | 0.72 | ADCY1 (0.69) | ADCY1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL22993988 | 0.71 | ADCY1 (0.67) | ADCY1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL22994220 | 0.71 | ADCY1 (0.67) | ADCY1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL24146220 | 0.70 | KDM4E (0.78) | ADCY1KDM4ESMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731964-B2 | Benzamide antibacterial agents | PURDUE RESEARCH FOUNDATION (US) | 2023-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11731964-B2 | Benzamide antibacterial agents | HDAC6, HDAC5, HDAC3 | ADCY1 4465/4885KDM4E 1365/4885SMN1; SMN2 2845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.