Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 5/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | WRN | Q14191 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22135513 | 0.83 | MGLL (0.33) | PTGS1PTGS2AKT1MGLLALDH1A1 | |
| SCHEMBL24340732 | 0.82 | MGLL (0.35) | PTGS1PTGS2AKT1MGLLMEN1 | |
| SCHEMBL24340762 | 0.82 | MGLL (0.32) | PTGS1PTGS2AKT1MGLLMEN1 | |
| SCHEMBL24340893 | 0.82 | MGLL (0.32) | PTGS1PTGS2AKT1MGLLMEN1 | |
| SCHEMBL20470974 | 0.80 | PTGS1 (0.39) | PTGS1PTGS2AKT1MGLLFAAH | |
| SCHEMBL23207887 | 0.79 | — | — | |
| SCHEMBL18544643 | 0.78 | AKT1 (0.31) | AKT1 | |
| SCHEMBL22135570 | 0.78 | — | — | |
| SCHEMBL24340793 | 0.78 | SMN1; SMN2 (0.41) | HPGDMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL24183327 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230256114-A1 | NOVEL MAYTANSINOIDS AS ADC PAYLOADS AND THEIR USE FOR THE TREATMENT OF CANCER | MEDPACE, INC. | 2023-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230256114-A1 | NOVEL MAYTANSINOIDS AS ADC PAYLOADS AND THEIR USE FOR THE TREATMENT OF CANCER | TPM3, MCHR2, CD2 | PTGS1 4590/4885PTGS2 3971/4885AKT1 2678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.