Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | PRCP | P42785 | 3/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24157610 | 0.81 | ESR1 (0.51) | ESR1ESR2GRIN1GRIN2BSIGMAR1 | |
| SCHEMBL25163142 | 0.79 | PRCP (0.44) | ESR1ESR2GRIN1GRIN2BSIGMAR1 | |
| SCHEMBL25163187 | 0.79 | PRCP (0.44) | ESR1ESR2GRIN1GRIN2BSIGMAR1 | |
| SCHEMBL24916723 | 0.79 | PRCP (0.44) | ESR1ESR2GRIN1GRIN2BSIGMAR1 | |
| SCHEMBL25163043 | 0.79 | PRCP (0.47) | ESR1ESR2GRIN1GRIN2BSIGMAR1 | |
| SCHEMBL2600445 | 0.79 | PRCP (0.47) | ESR1ESR2GRIN1GRIN2BSIGMAR1 | |
| SCHEMBL2600446 | 0.76 | PRCP (0.45) | ESR1ESR2PRCPCHRNA7 | |
| SCHEMBL12685723 | 0.76 | ESR1 (0.49) | ESR1ESR2GRIN1GRIN2BSIGMAR1 | |
| SCHEMBL28590256 | 0.76 | ESR1 (0.49) | ESR1ESR2GRIN1GRIN2BSIGMAR1 | |
| SCHEMBL24917154 | 0.76 | PRCP (0.45) | ESR1ESR2GRIN1GRIN2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8163944-B2 | Allylic oxidations catalyzed by dirhodium catalysts under aqueous conditions | UNIVERSITY OF MARYLAND COLLEGE PARK (US) | 2012-04-24 | — | — | US | disclosed |
| US-20090093638-A1 | Allylic Oxidations Catalyzed by Dirhodium Catalysts under Aqueous Conditions | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2009-04-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090093638-A1 | Allylic Oxidations Catalyzed by Dirhodium Catalysts under Aqueous Conditions | CYP11B2, DHCR7, ZDHHC7 | ESR1 488/4885ESR2 372/4885GRIN1 1809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.