Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 7/20 | 0.57 |
| ▸ | CNR1 | P21554 | 3/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 9/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26023104 | 0.81 | CNR2 (0.38) | CNR2CNR1 | |
| SCHEMBL26022788 | 0.79 | CNR2 (0.56) | CNR2CNR1KAT2BALDH1A1SMN1; SMN2 | |
| SCHEMBL26022881 | 0.79 | CNR2 (0.56) | CNR2CNR1KAT2BALDH1A1SMN1; SMN2 | |
| SCHEMBL26005328 | 0.79 | CNR2 (0.36) | CNR2CNR1KAT2BSMN1; SMN2RAB9A | |
| SCHEMBL26022933 | 0.76 | CNR2 (0.60) | CNR2CNR1KAT2BALDH1A1SMN1; SMN2 | |
| SCHEMBL26014006 | 0.76 | CNR2 (0.60) | CNR2CNR1KAT2BALDH1A1SMN1; SMN2 | |
| SCHEMBL17074594 | 0.73 | CNR2 (1.00) | CNR2CNR1KAT2BSMN1; SMN2GRM1 | |
| SCHEMBL27367745 | 0.72 | CNR2 (0.54) | CNR2CNR1KAT2BALDH1A1SMN1; SMN2 | |
| SCHEMBL26014019 | 0.71 | CNR2 (0.69) | CNR2CNR1KAT2BSMN1; SMN2GRM1 | |
| SCHEMBL25996086 | 0.70 | CNR2 (0.52) | CNR2CNR1KAT2BALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |