Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 1.00 |
| ▸ | CNR1 | P21554 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 7/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | BPTF | Q12830 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26014019 | 0.82 | CNR2 (0.69) | CNR2CNR1RAB9ASMN1; SMN2KAT2B | |
| SCHEMBL2324246 | 0.81 | CNR2 (1.00) | CNR2CNR1 | |
| SCHEMBL19000715 | 0.78 | CNR2 (0.64) | CNR2CNR1RAB9AGRM1 | |
| SCHEMBL15566620 | 0.75 | CNR2 (0.59) | CNR2CNR1RAB9ASMN1; SMN2KAT2B | |
| SCHEMBL26014006 | 0.75 | CNR2 (0.60) | CNR2CNR1RAB9ASMN1; SMN2KAT2B | |
| SCHEMBL26022933 | 0.75 | CNR2 (0.60) | CNR2CNR1RAB9ASMN1; SMN2KAT2B | |
| SCHEMBL9828687 | 0.74 | CNR2 (0.60) | CNR2CNR1RAB9ASMN1; SMN2GRM1 | |
| SCHEMBL26022888 | 0.73 | CNR2 (0.57) | CNR2CNR1RAB9ASMN1; SMN2KAT2B | |
| SCHEMBL10670539 | 0.73 | CNR2 (0.57) | CNR2CNR1RAB9ASMN1; SMN2KAT2B | |
| SCHEMBL9240157 | 0.73 | CNR2 (0.57) | CNR2CNR1RAB9ASMN1; SMN2KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2957560-A1 | PYRIDAZINE DERIVATIVES USEFUL AS CANNABINOID-2 AGONISTS | ALLERGAN, INC. (US) | 2015-12-23 | — | — | EP | disclosed |
| EP-2534137-B1 | PYRIDAZINE DERIVATIVES USEFUL AS CANNABINOID-2 AGONISTS | ALLERGAN INC (US) | 2015-09-16 | — | — | EP | disclosed |