Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23689771 | 0.88 | PIK3CD (0.53) | PIK3CDCYP1A2TDP1CYP2C19DRD3 | |
| SCHEMBL6960632 | 0.83 | PIK3CD (0.66) | PIK3CDCYP1A2TDP1CYP2C19DRD3 | |
| SCHEMBL27370876 | 0.81 | PIK3CD (0.69) | PIK3CDCYP1A2TDP1CYP2C19DRD3 | |
| SCHEMBL30800481 | 0.79 | PIK3CD (0.55) | PIK3CDCYP1A2TDP1CYP2C19DRD3 | |
| SCHEMBL22361388 | 0.79 | HSD17B10 (0.40) | CYP1A2CYP2C19USP2SIGMAR1 | |
| SCHEMBL23823660 | 0.78 | CYP1A2 (0.64) | PIK3CDCYP1A2TDP1DRD3HRH3 | |
| SCHEMBL23986518 | 0.77 | PIK3CD (0.58) | PIK3CDCYP1A2TDP1DRD3HRH3 | |
| SCHEMBL18708827 | 0.77 | SIGMAR1 (0.33) | KDM1AUSP2SIGMAR1ALDH1A1KDM4E | |
| SCHEMBL2619225 | 0.77 | CYP1A2 (0.56) | PIK3CDCYP1A2TDP1CYP2C19DRD3 | |
| SCHEMBL18911024 | 0.77 | SIGMAR1 (0.35) | USP2SIGMAR1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640248-B1 | AMINOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF | BEIJING ADAMADLE BIOTECHNOLOGY LLC (CN) | 2023-08-23 | — | — | EP | disclosed |