Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 10/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2602443 | 0.90 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL2618372 | 0.86 | NR1H2 (0.46) | PTGS2NR1H2NR1H3PTGS1 | |
| SCHEMBL2602440 | 0.85 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL2602438 | 0.85 | JAK2 (0.43) | PTGS2PTGS1 | |
| SCHEMBL2602444 | 0.85 | MAPK8 (0.43) | PTGS2 | |
| SCHEMBL2602442 | 0.85 | PTGS2 (0.42) | PTGS2PTGS1 | |
| SCHEMBL2602439 | 0.84 | PTGS2 (0.42) | PTGS2PTGS1 | |
| SCHEMBL2607446 | 0.81 | CYP1A2 (0.51) | PTGS2 | |
| SCHEMBL2602393 | 0.79 | PTGS2 (0.57) | PTGS2NR1H2NR1H3 | |
| SCHEMBL2602446 | 0.77 | PTGS2 (0.38) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095009-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | SPELMAN COLLEGE (US) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095009-A1 | SYNTHESIS AND ANTI-PROLIFERATIVE EFFECT OF BENZIMIDAZOLE DERIVATIVES | MKI67, CCNI, TYMP | PTGS2 606/4885NR1H2 4367/4885NR1H3 4518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.