Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5019115 | 0.83 | LMNA (0.50) | LMNAKDM4EGFERL3MBTL1HSD17B10 | |
| SCHEMBL12961297 | 0.82 | LMNA (0.51) | LMNAKDM4EGFERL3MBTL1HSD17B10 | |
| SCHEMBL26025189 | 0.78 | LMNA (0.46) | LMNAKDM4EGFERL3MBTL1HSD17B10 | |
| SCHEMBL6818984 | 0.78 | CACNA1H (0.46) | LMNAKDM4EGFERL3MBTL1HSD17B10 | |
| SCHEMBL30706635 | 0.76 | KDM4E (0.44) | LMNAKDM4EGFERL3MBTL1HSD17B10 | |
| SCHEMBL22084601 | 0.76 | KDM4E (0.47) | LMNAKDM4EGFERL3MBTL1HSD17B10 | |
| SCHEMBL26025432 | 0.74 | KDM4E (0.43) | LMNAKDM4EGFERL3MBTL1HSD17B10 | |
| SCHEMBL24276960 | 0.73 | KDM4E (0.41) | LMNAKDM4EGFERL3MBTL1HSD17B10 | |
| SCHEMBL24249420 | 0.72 | KDM4E (0.48) | LMNAKDM4EGFERL3MBTL1HSD17B10 | |
| SCHEMBL13073857 | 0.72 | CYP2D6 (0.53) | LMNAKDM4EGFERL3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154282-A1 | COMPOUNDS HAVING A T-STRUCTURE FORMED BY AT LEAST FOUR CYCLES FOR USE IN THE TREATMENT OF CANCER AND OTHER INDICATIONS | THERAS, INC. (US) | 2023-08-17 | — | — | WO | disclosed |