Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 3/20 | 0.56 |
| ▸ | PARP1 | P09874 | 8/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.47 |
| ▸ | TNKS | O95271 | 2/20 | 0.46 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25363012 | 1.00 | HPGDS (0.56) | HPGDSPARP1PARP2TNKSTNKS2 | |
| SCHEMBL30496093 | 0.95 | HPGDS (0.57) | HPGDSPARP1TNKSTNKS2USP30 | |
| SCHEMBL25363420 | 0.95 | HPGDS (0.57) | HPGDSPARP1TNKSTNKS2USP30 | |
| SCHEMBL30496019 | 0.94 | HPGDS (0.55) | HPGDSPARP1TNKSTNKS2GPR119 | |
| SCHEMBL7718379 | 0.94 | HPGDS (0.55) | HPGDSPARP1TNKSTNKS2GPR119 | |
| SCHEMBL26911916 | 0.91 | HPGDS (0.46) | HPGDSPARP1KDM4E | |
| SCHEMBL25362749 | 0.90 | PARP1 (0.51) | HPGDSPARP1GPR119KDM4EMAPT | |
| SCHEMBL25363414 | 0.90 | PARP1 (0.51) | HPGDSPARP1GPR119KDM4EMAPT | |
| SCHEMBL26025078 | 0.90 | PARP1 (0.51) | HPGDSPARP1GPR119KDM4EMAPT | |
| SCHEMBL25430145 | 0.89 | HPGDS (0.47) | HPGDSPARP1GPR119USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4674841-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2026-01-07 | — | — | EP | disclosed |
| CN-118973578-A | Pharmaceutical compounds | 杜克街生物有限公司 | 2024-11-15 | — | — | CN | disclosed |
| EP-4444305-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2024-10-16 | — | — | EP | disclosed |
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023156386-A2 | PHARMACEUTICAL COMPOUND | Duke Street Bio Limited (GB) | 2023-08-24 | — | — | WO | disclosed |