Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25364560 | 0.91 | NPC1 (0.42) | NPC1RAB9ATRPV4HSD11B1TSHR | |
| SCHEMBL26027274 | 0.90 | ATM (0.43) | TRPV4HSD11B1FASNMAPTHTT | |
| SCHEMBL25364701 | 0.89 | TRPV4 (0.40) | NPC1RAB9ATRPV4FASNMAPT | |
| SCHEMBL25364699 | 0.89 | TRPV4 (0.40) | NPC1RAB9ATRPV4FASNMAPT | |
| SCHEMBL25363368 | 0.89 | CNR1 (0.46) | LMNASMN1; SMN2CNR1HTR7L3MBTL1 | |
| SCHEMBL25364135 | 0.89 | CNR1 (0.46) | LMNASMN1; SMN2CNR1HTR7L3MBTL1 | |
| SCHEMBL25363361 | 0.89 | CNR1 (0.46) | LMNASMN1; SMN2CNR1HTR7L3MBTL1 | |
| SCHEMBL25365359 | 0.88 | NPC1 (0.39) | NPC1RAB9ATRPV4FASNMAPT | |
| SCHEMBL30539989 | 0.88 | NPC1 (0.39) | NPC1RAB9ATRPV4FASNMAPT | |
| SCHEMBL26025566 | 0.88 | TRPV4 (0.43) | TRPV4HSD11B1ALKTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023154499-A1 | EMOPAMIL-BINDING PROTEIN INHIBITORS AND USES THEREOF | BIOGEN MA INC. (US) | 2023-08-17 | — | — | WO | disclosed |