SCHEMBL26028481

SCHEMBL26028481

Brc1ccccc1-c1ccccc1C1=CCCC=C1

nearest known ligand 0.38

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38
MAPK1 P28482 1/20 0.38
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
PBRM1 Q86U86 1/20 0.30
IDO1 P14902 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22994268 0.92 ALDH1A1 (0.40) ALDH1A1MAPK1MAOAMAOBPBRM1
SCHEMBL21338024 0.77 ALDH1A1 (0.35) ALDH1A1MAPK1
SCHEMBL13706531 0.75 CYP2A6 (0.31) ALDH1A1MAPK1MAOAMAOB
SCHEMBL29720090 0.73 CYP2A6 (0.40) ALDH1A1MAOBIDO1LMNA
SCHEMBL12992750 0.73 ALDH1A1 (0.46) ALDH1A1IDO1
SCHEMBL30102614 0.73 HSD17B10 (0.40) ALDH1A1MAPK1IDO1LMNA
SCHEMBL18822054 0.73
SCHEMBL13523400 0.73
SCHEMBL31465796 0.72 ALDH1A1 (0.63) ALDH1A1MAPK1MAOAMAOBPBRM1
SCHEMBL7519287 0.72 ALDH1A1 (0.63) ALDH1A1MAPK1MAOAMAOBPBRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023140285-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2023-07-27 WO disclosed