Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.46 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16839755 | 0.82 | ALDH1A1 (0.47) | ALDH1A1GAACD274 | |
| SCHEMBL2870 | 0.81 | MYC (0.47) | MYCWDR5MMEFFAR1AKR1B1 | |
| SCHEMBL2132 | 0.81 | MYC (0.47) | MYCWDR5MMEFFAR1AKR1B1 | |
| SCHEMBL3121 | 0.80 | MYC (0.43) | MYCWDR5MMEFFAR1AKR1B1 | |
| SCHEMBL2465 | 0.80 | MYC (0.43) | MYCWDR5MMEFFAR1AKR1B1 | |
| SCHEMBL2103 | 0.80 | MYC (0.47) | MYCWDR5MMENLRP3FFAR1 | |
| SCHEMBL8936169 | 0.80 | PPID (0.55) | ALDH1A1L3MBTL1PPARGMAPT | |
| SCHEMBL536970 | 0.80 | PPID (0.55) | ALDH1A1L3MBTL1PPARGMAPT | |
| SCHEMBL8239406 | 0.79 | MME (0.45) | MYCWDR5MMEFFAR1AKR1B1 | |
| SCHEMBL10057911 | 0.79 | MME (0.45) | MYCWDR5MMEFFAR1AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965592-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1999-10-12 | — | — | US | disclosed |
| US-5399578-A | Hypotensive; valsartan; high blood pressure and cardiac insufficiency | CIBA-GEIGY CORP (US) | 1995-03-21 | — | — | US | disclosed |